英语翻译The effect of the molecular weight of the hydrophilic ma

英语翻译
The effect of the molecular weight of the hydrophilic macro-CTAused (i.e.,the chain length of the grafted polymer brushes) on the equilibrium binding properties of the resulting MIPs and CPs in river water and diluted biological samples was also investigated.It can be seen clearly that,in contrast to the MIP nanoparticles grafted with relatively long PHEMA brushes (Mn,NMR=4800),those bearing shorter PHEMA brushes (Mn,NMR=2440 and 3250) could only specifically recognize the template in river water,whereas their specific template binding (Figure 3b; see also Figure S7b,c) and selectivity towards the template (see Figure S14b,c and Table S3) almost disappeared in the diluted milk and bovine serum.These results suggest that the chain length of the hydrophilic polymer brushes played a decisive role in the compatibility of the grafted MIP nanoparticles with biological samples,and that only those polymer brushes with a high enough molecular weight could act as an efficient hydrophilic protective shield for the MIP nanoparticles to prevent the accumulation of proteins on their surface and enable them to function properly.[10b,c] As expected,the ungrafted MIP hardly showed any specific template binding in river water or diluted biological solutions (Figure 3b; see also Figures S7aand S14aand Table S3).