英语翻译RNA Polymerase IV DirectsSilencing of Endogenous DNAPlan
英语翻译
RNA Polymerase IV DirectsSilencing of Endogenous DNA
Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition tothe well-known DNA-dependent RNA polymerases I,II,and III.By mutation ofthe two largest subunits (NRPD1a and NRPD2),we show that Pol IV silencescertain transposons and repetitive DNA in a short interfering RNA pathwayinvolving RNA-dependent RNA polymerase 2 and Dicer-like 3.The existenceof this distinct silencing polymerase may explain the paradoxical involvementof an RNA silencing pathway in maintenance of transcriptional silencing.
RNA Polymerase IV DirectsSilencing of Endogenous DNA
Plants encode subunits for a fourth RNA polymerase (Pol IV) in addition tothe well-known DNA-dependent RNA polymerases I,II,and III.By mutation ofthe two largest subunits (NRPD1a and NRPD2),we show that Pol IV silencescertain transposons and repetitive DNA in a short interfering RNA pathwayinvolving RNA-dependent RNA polymerase 2 and Dicer-like 3.The existenceof this distinct silencing polymerase may explain the paradoxical involvementof an RNA silencing pathway in maintenance of transcriptional silencing.
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