lht2719
幼苗
共回答了16个问题采纳率:93.8% 举报
Sulforaphane is found in vegetables, anti-cancer ability to one of the best active ingredient, it does not exist in vegetables directly, but rather in chewing or the harvest by the release of myrosinase digestion of a isothiocyanates compounds. It has extensive biological activity, such as can be induced to body good Ⅱ phase enzyme activity, the activity of the enzyme inhibition Ⅰ phase, thus effectively prevent cancer, in addition to strong light protection, and cancer incidence in recent years, more and more high, so the radish sulfur has broad market prospect, more and more aroused people's concern. This paper use chemical synthesis method of synthesis of sulforaphane, a series of derivatives with 1, 4 - dibromobutane with phthalates formyl imine potassium reacts alkanes, after reaction with thioacetic acid potassium generated ester, the ester catalyzed by acid hydrolysis is mercaptan this important intermediates, mercaptan and different bromine generation reaction sulfur ether, by Gabriel, primary amine, primary amine and carbon disulfide, methyl sulfonyl chloride reaction generates isothiocyanates, finally with the m - CPBA oxidation sulforaphane derivatives, antitumor activity by determined by MTT method after testing.
1年前
5