Which hotel I should stay in L.A.

Which hotel I should stay in L.A.
I'm planning to travel to L.A.U.S.for about 10 days.I plan to join local tour for 7 days and travel by myself for 3-4 days.1.Please suggest which hotel I should stay,so that I can join the tour easily and can travel around with public transport (e.g.metrolink) easily?2.Anyone has experience and got the trip plan,e.g.Day 1,Day 2...and with transport info,please provide,(P.S.I don't really want to go to Disney and Universial studio as I will go to Orlando)MANY THANKS.