英语翻译麻烦帮我翻译下这段文字:盐酸左西替利嗪(Levocetirizine Hydrochloride)是西替利嗪(C

英语翻译
麻烦帮我翻译下这段文字:
盐酸左西替利嗪(Levocetirizine Hydrochloride)是西替利嗪(Cetirizine)的活性对映体,为新的第2代抗组胺药,具有H1-受体的高亲和力和选择性,同时能抑制变态反应相关的多种炎症介质的释放而起到较广泛抗炎作用,为优秀的治疗过敏性鼻炎的药物.目前临床上使用的大多为口服制剂,主要是通过胃肠道吸收后,再通过血液循环全身分布,从而拮抗炎症介质组胺的作用,达到治疗全身过敏性炎症的作用.过敏性鼻炎为鼻粘膜局部过敏,全身给药的方式局部血药浓度低,而且口服途径大剂量应用可能存在严重的全身不良反应的危险,并非一种最理想的给药方式.本研究结合盐酸左西替利嗪的理化性质和药理作用特点,研制了鼻腔喷雾剂,通过局部给药,增加机体过敏炎症部位的局部组织游离药物浓度,可有效拮抗组胺的致敏作用,更好发挥其局部抗过敏和抗炎疗效,降低不良反应.
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Left hydrochloride cetirizine (Levocetirizine Hydrochloride) is Cetirizine triazine (Cetirizine) activity of enantiomers,as a new second-generation antihistamines,H1-receptor with high affinity and selectivity.also can inhibit allergic inflammation related to the various media and the release of anti-inflammatory play a wider role for the excellent treatment of allergic rhinitis medication.Clinical use mostly oral formulations,mainly through the gastrointestinal absorption,through the distribution of systemic blood circulation,thereby inflammatory mediators histamine antagonist role achieve systemic treatment of allergic inflammation.Allergic rhinitis for partial nasal allergies,systemic administration of local low plasma concentrations,but large doses of the oral route application potentially serious systemic adverse reactions dangerous,is not an ideal way of administration.The combination left hydrochloride cetirizine the physical and chemical properties and pharmacological characteristics of the role,a nasal spray developed by local administration.allergic inflammation increases the body parts of the local organization of free drug concentration to be effective antagonist of histamine allergens,better play to their local anti-allergic and anti-inflammatory effects and reduce adverse reactions

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